Dispersant for Pharmaceuticals

A dispersant for pharmaceuticals is a critical pharmaceutical excipient whose primary function is to ensure the uniform and stable dispersion of hydrophobic active pharmaceutical ingredients in liquid media, thereby forming a homogeneous suspension system. In oral suspensions, injectable suspensions, or topical preparations, insoluble drug particles tend to aggregate and settle due to high surface energy, leading to dosing inaccuracies. Through their amphiphilic structure, dispersants anchor onto drug particle surfaces and effectively prevent aggregation via electrostatic repulsion or steric hindrance, maintaining uniform suspension during storage. This characteristic not only guarantees dosing accuracy and uniformity while enhancing physical stability and shelf life, but also helps improve drug dissolution properties, potentially increasing bioavailability. Therefore, dispersants complying with pharmacopoeial standards are essential for ensuring drug safety, efficacy, and quality controllability.

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